Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally-Occurring Epilepsy
Barriers to developing treatments for human status epilepticus (SE) include the inadequacy of experimental animal models.In contrast, naturally-occurring canine epilepsy is similar to the human condition and can serve as a platform to translate research from rodents to humans.The objectives of this study were to characterize the pharmacokinetics (P